One person was killed in an attack by gunmen at a nightclub in Cincinnati, Ohio, which also left at least 14 people injured.
Cincinnati Police Department say there has been no indication that the shooting was terror-related.
Several people have life-threatening injuries, Mr Neudigate told news channel WLWT-TV.
“We are in the middle of a very horrific situation that occurred at the nightclub with multiple victims. It’s going to be a long night for our homicide units to investigate,” he said.
Police Captain Kimberly Williams said the gunmen were still at large and the force did not have good descriptions of them. Witnesses had been reluctant to co-operate, she added.
“At this point it’s unclear exactly what instigated the shooting,” Capt Williams told reporters. “We believe that there were at least a couple of shooters involved.”
The shooting happened at about 01:00 (05:00 GMT) while hundreds of people were in the venue.
The shooting comes less than a year after gunman Omar Mateen opened fire at a gay nightclub in Orlando, Florida.
Mateen killed 49 people in the deadliest mass shooting in US history.